16 Top Vitamin B12 Supplements for Dogs

Discover the best vitamin B12 supplement for dogs with our quick, trusted guide to boost your pup's health and vitality effortlessly.
BrandMy RatingPrice
Nutrition Strength
Best Price-to-Performance
7.8/10
Nutramax Laboratories
Best for Large Dogs
9.6/10
Nutramax Laboratories
Best for Small Dogs
9.4/10
Petlab Co.
Best for Long-Term Use
8.8/10
Wonder Laboratories
9.4/10

Best Vitamin B12 Supplement for Dogs

Looking for the perfect B12 boost to keep your furry friend lively and thriving? With a myriad of supplements swirling in the market, finding the best vitamin B12 supplement for dogs can feel like searching for a needle in a haystack. Fear not — we’ve sliced through the noise to reveal the top choices that will support your pup’s health with simplicity and style.

Best Price-to-Performance: Nutrition Strength B Complex

Vitamin B for Dogs, Complete B Complex for Dogs, Promote Blood Cell & Nervous System Health, Help Sustain Cellular Energy Production & Maintain Brain Function, 120 Chewable Tablets
Highlights
Supports brain and nervous health
High quality USA-made
Supports energy production

Our team chose this as the "Best Price-to-Performance" because it strikes an excellent balance between quality and affordability.

These tablets are packed with a comprehensive range of B vitamins, supporting everything from energy production to nervous system health — all delivered in a human-grade, USA-made supplement.

While some dogs may dislike the flavor or smell, many pet owners appreciate the thoughtful formulation that covers vital functions like blood health and cognitive support.

Overall, this supplement offers fantastic value for long-term use, especially if you're seeking reliable B12 support at a wallet-friendly price.

Be sure to also check out the best mineral supplement for water for more options! Also, here is the price history so you know exactly when to buy!

Price history for Nutrition Strength B Complex on Amazon

Best for Large Dogs: Nutramax Cobalequin B12 Supplement

Nutramax Laboratories Cobalequin B12 Supplement for Medium to Large Dogs, 45 Chewable Tablets, Hydrolyzed Chicken, 2.08 ounces
Highlights
Easy to administer
Vet recommended
Supports health & energy

Nutramax Cobalequin is specifically formulated for medium to large dogs, making it an ideal choice for bigger breeds that need that extra B12 boost.

The chewable tablets are a breeze to give—crushed or whole, they slip right in without fuss.

Since it's vet-recommended and backed by science, you can trust that your furry friend is getting a high-quality, safe supplement designed to support energy and overall health.

While the price might be on the higher side and it’s tailored to certain sizes, the convenience and tailored approach make it a standout for large dogs needing B12 support.

Be sure to also check out the best iron supplement for cats for more options! Also, here is the price history so you know exactly when to buy!

Price history for Nutramax Cobalequin B12 Supplement on Amazon

Best for Small Dogs: Cobalequin

Nutramax Cobalequin B12 Supplement for Cats and Small Dogs, 45 Count (Pack of 1)
Highlights
Vet recommended formula
Easy to serve tablets
Supports overall health

Nutramax Cobalequin is specifically designed for small dogs and cats, making it a perfect fit for our petite friends.

The vet-recommended formula gives us confidence in its safety and effectiveness while supporting overall health with ease.

The easy-to-serve tablets can be crushed or given whole, simplifying daily administration—no more fussing over complicated doses.

Although the flavor options are limited, the convenience and trusted brand reputation make it a top pick for pet owners seeking a reliable B12 supplement tailored for small breeds.

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Price history for Cobalequin on Amazon

Best for Long-Term Use: PetLab Co Dog Multivitamin

PetLab Co. 22 in 1 Dog Multivitamin - Support Dog's Immune Response, Skin, Coat, Joints & Overall Health - Vitamins A, E, D, B12, Minerals, Antioxidants - Chewable Pork Flavor
Highlights
Dog loves Pork flavor
Shiny coat & healthy skin
Supports overall health

PetLab Co.’s Dog Multivitamin Chews are a fantastic choice for long-term health support.

The 13 unique benefits make these chews a versatile, all-in-one solution — from boosting your pup's immune system to enhancing their coat shine.

The delicious pork flavor is a hit, making daily doses a treat rather than a chore.

Plus, with a broad spectrum of 22 vitamins, including B12, they provide a comprehensive nutritional boost.

While some small dogs may require less, overall, these chews are a premium, US-made product — a solid pick to keep your dog thriving over the years.

Be sure to also check out the best joint supplement for dachshunds for more options! Also, here is the price history so you know exactly when to buy!

Price history for PetLab Co Dog Multivitamin on Amazon

Wonder Laboratories Pet Factor Vitamin B12

Pet Factor B-12 | Vitamin B-12 in Methylcobalamin Form | Popular in Treatment of EPI in Dogs 180 Capsules
Highlights
Recommended by experts
Enhances B-12 absorption
Made in USA

Wonder Laboratories' Pet Factor Vitamin B12 is a solid choice for dogs needing a boost in B-12, especially for those with EPI.

Recommended by the experts at Epi4Dogs, it naturally enhances absorption, ensuring your pup gets the most out of every dose.

Made right here in the USA in a GMP-certified facility, it offers peace of mind on quality.

The capsules are easy to give, though they can be a bit messy, so patience is key.

Perfect for all breed sizes and life stages, this supplement offers great value with 180 capsules per bottle.

Be sure to also check out the best zinc supplement for goats for more options! Also, here is the price history so you know exactly when to buy!

Price history for Wonder Laboratories Pet Factor Vitamin B12 on Amazon

Wonder Paws B12

B12 Supplement for Dogs – Vitamin B-12 for Dogs of All Ages, Sizes & Breeds – Vitamin B12 for Dogs as Superior Methylcobalamin, Cobalamin & Folate (5-MTHF) – 90 Beef Flavored Chewables
Highlights
Highly absorbable methyl B12
Supports immune & nervous health
Tasty beef flavor

Wonder Paws offers a powerful combination of two B12 forms—cobalamin and methylcobalamin—which ensures superior absorption and effectiveness.

The tasty beef flavor makes it easy to administer, even for picky pups.

Plus, the inclusion of active folate (5-MTHF) adds extra support for immune health, brain function, and metabolism.

While it is a bit pricier and requires daily dosing, the quality control from NASC certification and USA manufacturing assures safety and reliability.

Overall, this supplement is a smart choice for dogs needing B12 boost and overall vitality.

Be sure to also check out the best joint supplement for dogs with allergies for more options! Also, here is the price history so you know exactly when to buy!

Price history for Wonder Paws B12 on Amazon

Rx Vitamins B12 Vitamin B12 Supplement for Dogs

Rx Vitamins Rx B12 for Dogs & Cats - Vitamin B12 Liquid Supplement for Pets - Dog Vitamins for Small & Large Breed - Cat Health Supplies - 4 oz.
Highlights
Supports energy and vitality
Easy to administer liquid
Suitable for all breeds

Rx Vitamins B12 for Dogs & Cats is a premium liquid supplement that makes it incredibly easy to give your pet their daily dose.

Its high-potency formula is designed by veterinarians, ensuring safety and effectiveness for all life stages.

The liquid form is perfect for disguising in food, which can make administration smoother—even for picky eaters.

While some pets may take a few weeks to show results and might resist the taste initially, with consistent use, this supplement can support your pet’s energy, vitality, and immune health.

A solid choice for pet owners seeking high-quality B12 support!

Be sure to also check out the best allergy supplements for dogs for more options! Also, here is the price history so you know exactly when to buy!

Price history for Rx Vitamins B12 on Amazon

Wonder Laboratories Pet Factor B-12

Pet Factor B-12 | Vitamin B-12 in Methylcobalamin Form | Popular in Treatment of EPI in Dogs. 90 Count
Highlights
Bioavailable methylcobalamin B-12
Supports digestion and absorption
Made in the USA

Wonder Laboratories' B-12 supplement is a popular choice for pets with EPI and is officially recommended by the Epi4Dogs Foundation.

The bioavailable methylcobalamin form supports optimal absorption and improves digestion, which is crucial for dogs with absorption issues.

Made in the USA in an FDA-registered facility, it meets high safety standards.

While it works wonderfully for smaller to medium dogs, larger breeds might see slower results.

Plus, it has no added flavors, so some dogs may take a little longer to warm up to it.

Overall, a solid, well-crafted option for canine B-12 needs.

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Price history for Wonder Laboratories Pet Factor B-12 on Amazon

Nutrition Strength B12 for Dogs

Vitamin B12 for Dogs Plus Folate & Calcium, Support the Nervous System & Blood Cell Formation, Help Sustain Cellular Energy Generation & Maintain DNA Synthesis, 120 Chewable Tablets
Highlights
Supports blood cell formation
Natural methylcobalamin form
High customer satisfaction

Nutrition Strength's vitamin B12 for dogs is a top-tier choice for supporting your pup’s blood health and energy levels.

The supplement supplies methylcobalamin, the biologically active form of B12, ensuring optimal absorption and effectiveness.

Plus, it’s packed with folic acid and calcium, which promote cognitive health and cardiovascular function.

The tablets are easy to feed—mix them into food or give directly—making supplementation hassle-free.

With a stellar 4.3-star rating and a 365-day guarantee, it’s clear that many pet owners trust and love this high-quality, USA-made product for their furry friends.

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Price history for Nutrition Strength B12 for Dogs on Amazon

iVitamins Vitamin B12 Supplement for Dogs

Vitamin B for Dogs | Vitamin B Complex for Dogs | Vitamin B12 for Dogs | Dog Vitamins | B12 Vitamins for Dogs | Vitamin B Dog Supplements | B Complex for Dogs | B12 for Dogs | Do1 fl oz: Bacon Flavor
Highlights
Supports overall health
Delicious bacon flavor
For all dog sizes

The delicious bacon flavor makes it easy to administer, and dogs seem to love it!

Its comprehensive support promotes overall health, helping with cellular health, energy levels, and brain function.

Plus, it's suitable for all breeds and sizes, ensuring easy digestibility and quick absorption.

While some users reported mixed effectiveness, its gentle, natural approach makes it a great choice for pet owners seeking a tasty supplement with confidence in quality — especially since it's proudly USA-made.

Overall, a solid option to support your dog's vitality.

Be sure to also check out the best liquid joint supplement for dogs for more options! Also, here is the price history so you know exactly when to buy!

Price history for iVitamins on Amazon

Infinite Health Labs

Liquid Vitamin B-12 for Dogs and Cats - Vet Formulated - Effective for All Animals Methylcobalamin (Methyl B12) - Energy, Appetite and Mood - Made in USA
Highlights
Shows quick energy boost
Helps with mood improvement
Made in USA

The Infinite Health Labs Liquid Vitamin B-12 delivers a noticeable quick energy boost and can help lift your pup’s mood, making daily walks and playtime more enjoyable.

The bioactive methylcobalamin form means your dog absorbs it efficiently, showing faster results.

Made right here in the USA, it offers peace of mind about quality.

However, some users may have concerns about ingredient transparency and the limited appetite support.

Overall, if you're seeking a reliable, vet-approved B12 supplement to boost your dog's vitality, this one's definitely worth considering.

Be sure to also check out the best cranberry supplement for dogs uti for more options! Also, here is the price history so you know exactly when to buy!

Price history for Infinite Health Labs on Amazon

Ka'Dee Simply Beyouful

Liquid Vitamin B-12 Complex Drops for Dogs and Cats - Nutritionally Balanced Vet Formulated - Energy, Appetite, Mood - Recovery - Helps Cognition and Brain, Joints, Skin, Digestion
Highlights
Easy to administer
Supports healthy coat
Long-lasting bottle

The Ka'Dee Simply Beyouful B12 drops are a great choice for pet owners seeking a convenient liquid supplement.

The formula offers a well-balanced mix of antioxidants, vitamins, and minerals, making it ideal for supporting overall pet health.

We love how easy it is to mix with food or water, saving time and hassle during daily routines.

Plus, the support for a shiny, healthy coat is a definite bonus.

While some might find the smell a bit strong and the flavor varies, the long-lasting bottle and adaptability for dogs and cats make this a standout option.

Be sure to also check out the best cranberry supplement for cats for more options! Also, here is the price history so you know exactly when to buy!

Price history for Ka'Dee Simply Beyouful on Amazon

Rx Vitamins Amino B Plex Vitamin B12 Supplement for Dogs

Rx Vitamins Amino B Plex for Pets - B Vitamin Complex Plus Amino Acids for Dogs & Cats - Vitamin Supplements for Dogs' & Cats' Total Body Support - 2 oz.
Highlights
Easy to dose drops
Tasty and palatable
Supports energy levels

The easy-to-dose drops make it a breeze to add to your dog’s food, even on busy mornings.

Its tasty aroma means most pups actually beg for their daily dose, making supplementation less of a chore.

The inclusion of spirulina elevates this formula with an array of nutrients that support your dog’s energy and vitality — especially beneficial for active or senior pets.

While it has a strong smell that might take some getting used to, the subtle yet noticeable boost in energy makes it worth trying.

Overall, this liquid B vitamin complex is a quality choice for maintaining your dog’s health.

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Price history for Rx Vitamins Amino B Plex on Amazon

Nutrition Strength Iron Chewables

Iron for Dogs with Anemia to Support Blood Health, Blood Cell Formation & Oxygen Supply, Iron Supplement for Anemic Dogs + Vitamin C, Folate, Vitamin B12, 120 Chewable Tablets
Highlights
Supports blood health
Made in the USA
Effective for anemia

Nutrition Strength's iron for dogs tablets are a highly-rated supplement designed to support blood health and combat anemia in pets of all sizes.

The carefully formulated blend, enriched with vitamin B12, folate, and vitamin C, ensures that your dog receives essential nutrients for red blood cell production and oxygen transport.

Made right here in the USA, these tablets adhere to strict manufacturing standards, providing peace of mind.

While some dogs may be a tad picky with taking pills, the benefits of improved energy and overall vitality make this supplement worth trying.

Be sure to also check out the best berberine supplement for sibo for more options! Also, here is the price history so you know exactly when to buy!

Price history for Nutrition Strength Iron Chewables on Amazon

Golden Paw Multivitamin

Liquid Multivitamin for Dogs | 10-in-1 Multivitamin for Cats | Vitamin B Complex for Cats & Dogs | Cranberry Supplement | for Urination, Digestion, Breathing & Movement | for All Pets Ages | 2 Oz
Highlights
Natural ingredients
Easy liquid form
Suitable for all breeds

The natural ingredients shine, offering a wholesome blend that supports your pet’s overall health—from digestion to joint mobility.

The liquid form makes dosing quick and hassle-free, perfect for pets who dislike capsules.

It’s suitable for all breeds and ages, ensuring every furry friend gets the care they deserve.

While the short shelf life requires prompt use, the convenience of dropping the supplement directly into your pet’s mouth or food outweighs the minor downside.

Overall, this multivitamin is a fantastic all-in-one solution for maintaining your pet’s vitality with love and natural care.

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Price history for Golden Paw Multivitamin on Amazon

LAORICI Iron Supplement Vitamin B12 Supplement for Dogs

Iron Supplement for Cats & Dogs - Liquid Iron with Vitamin C and B12, Improves Anaemia, Low Energy & Lethargy in Pets, Promotes Blood Health, Red Blood Cell Formation, Enhances Vitality
Highlights
Fast absorption
Easy to administer
Supports red blood cells

The liquid iron supplement from LAORICI is a game-changer for pet owners concerned about anemia and low energy in their dogs.

Its gentle, fast-absorbing formula ensures that your furry friend gets the nutrients they need without stomach upset or discomfort.

The dropper design makes administration super easy and stress-free, even for the pickiest pets.

Plus, since it can be mixed with food or water, it's perfect for maintaining a happy, active pup.

While it's not dog-specific, its effectiveness and ease of use earn it a solid spot on our list.

Be sure to also check out the best calcium supplement for celiacs for more options! Also, here is the price history so you know exactly when to buy!

Price history for LAORICI Iron Supplement on Amazon

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